All states (except Washington) plus DC now offer a state sponsored 529 Savings Plan (Wyoming participates with Colorado).  The plan(s) offered by the state in which you live may or may not meet your needs or preferences.  You may select a plan from any state that does not require you or the beneficiary to be a resident to open the account.  The residency requirements only apply at the time the account is opened.  Once it is established you may continue to invest in the plan regardless of where you live.  A tuition savings plan enables the account value to be used to pay qualified expenses at over 4,000 educational institutions across the US.  It is safe to say your child may go to school in any state and have expenses paid from a 529 program that is not sponsored by the state where the child is a student and also the plan not be sponsored by the state where you live.  In simple terms - it is your money and it can be used at any higher education institution that is approved to participate in Title IV Federal Student Aid Programs - and there aren't many U.S. based colleges that don’t participate.